| February 18, 2022 | ||
| SønderjyskE | 20:00 | AGF |
| February 20, 2022 | ||
| Midtjylland | 15:00 | AaB |
| Silkeborg | 15:00 | Vejle |
| Nordsjælland | 17:00 | Brøndby |
| FC Copenhagen | 19:00 | OB |
| February 21, 2022 | ||
| Randers | 20:00 | Viborg |
| February 25, 2022 | ||
| Vejle | 20:00 | AGF |
| February 27, 2022 | ||
| AaB | 15:00 | Silkeborg |
| Nordsjælland | 15:00 | Randers |
| Viborg | 17:00 | FC Copenhagen |
| OB | 19:00 | Midtjylland |
| February 28, 2022 | ||
| Brøndby | 20:00 | SønderjyskE |
| March 4, 2022 | ||
| Midtjylland | 19:00 | Viborg |
| FC Copenhagen | 21:00 | Randers |
| March 6, 2022 | ||
| SønderjyskE | 15:00 | OB |
| AaB | 17:00 | Vejle |
| Silkeborg | 19:00 | Brøndby |
| March 7, 2022 | ||
| AGF | 20:00 | Nordsjælland |
| March 11, 2022 | ||
| Nordsjælland | 20:00 | SønderjyskE |
