| November 22, 2020 | ||
| 1. FC Köln | 1 - 2 | Union Berlin |
| SC Freiburg | 1 - 3 | 1. FSV Mainz 05 |
| November 21, 2020 | ||
| Hertha BSC | 2 - 5 | Borussia Dortmund |
| Eintracht Frankfurt | 1 - 1 | RB Leipzig |
| Arminia Bielefeld | 1 - 2 | Bayer 04 Leverkusen |
| Schalke 04 | 0 - 2 | Wolfsburg |
| TSG 1899 Hoffenheim | 3 - 3 | Stuttgart |
| Borussia Mönchengladbach | 1 - 1 | Augsburg 1907 |
| Bayern Munich | 1 - 1 | Werder Bremen |
| November 8, 2020 | ||
| Bayer 04 Leverkusen | 4 - 3 | Borussia Mönchengladbach |
| Wolfsburg | 2 - 1 | TSG 1899 Hoffenheim |
| November 7, 2020 | ||
| Borussia Dortmund | 2 - 3 | Bayern Munich |
| 1. FSV Mainz 05 | 2 - 2 | Schalke 04 |
| Union Berlin | 5 - 0 | Arminia Bielefeld |
| RB Leipzig | 3 - 0 | SC Freiburg |
| Augsburg 1907 | 0 - 3 | Hertha BSC |
| Stuttgart | 2 - 2 | Eintracht Frankfurt |
| November 6, 2020 | ||
| Werder Bremen | 1 - 1 | 1. FC Köln |
| November 2, 2020 | ||
| TSG 1899 Hoffenheim | 1 - 3 | Union Berlin |
