| October 2, 2022 | ||
| Sassuolo | 5 - 0 | Salernitana |
| Sampdoria | 0 - 3 | Monza |
| Lecce | 1 - 1 | Cremonese |
| Lazio | 4 - 0 | Spezia |
| October 1, 2022 | ||
| Empoli | 1 - 3 | AC Milan |
| Inter Milan | 1 - 2 | Roma |
| SSC Napoli | 3 - 1 | Torino |
| September 18, 2022 | ||
| AC Milan | 1 - 2 | SSC Napoli |
| Roma | 0 - 1 | Atalanta |
| Monza | 1 - 0 | Juventus |
| Fiorentina | 2 - 0 | Verona |
| Cremonese | 0 - 4 | Lazio |
| Udinese | 3 - 1 | Inter Milan |
| September 17, 2022 | ||
| Torino | 0 - 1 | Sassuolo |
| Spezia | 2 - 1 | Sampdoria |
| Bologna | 0 - 1 | Empoli |
| September 16, 2022 | ||
| Salernitana | 1 - 2 | Lecce |
| September 12, 2022 | ||
| Empoli | 1 - 2 | Roma |
