| May 9, 2021 | ||
| Hellas Verona | 1 - 1 | Torino |
| Benevento | 1 - 3 | Cagliari |
| Parma | 2 - 5 | Atalanta |
| Genoa | 1 - 2 | Sassuolo |
| May 8, 2021 | ||
| Fiorentina | 2 - 0 | Lazio |
| Inter Milan | 5 - 1 | Sampdoria |
| Udinese | 1 - 1 | Bologna |
| Spezia | 1 - 4 | SSC Napoli |
| May 3, 2021 | ||
| Torino | 1 - 0 | Parma |
| May 2, 2021 | ||
| Sampdoria | 2 - 0 | Roma |
| Udinese | 1 - 2 | Juventus |
| Bologna | 3 - 3 | Fiorentina |
| SSC Napoli | 1 - 1 | Cagliari |
| Sassuolo | 1 - 1 | Atalanta |
| Lazio | 4 - 3 | Genoa |
| May 1, 2021 | ||
| Milan | 2 - 0 | Benevento |
| Crotone | 0 - 2 | Inter Milan |
| Hellas Verona | 1 - 1 | Spezia |
| April 26, 2021 | ||
| Lazio | 3 - 0 | Milan |
| Torino | 0 - 2 | SSC Napoli |
