| September 26, 2020 | ||
| Torino | 15:00 | Atalanta |
| Cagliari | 18:00 | Lazio |
| Sampdoria | 18:00 | Benevento |
| Inter Milan | 20:45 | Fiorentina |
| September 27, 2020 | ||
| Spezia | 12:30 | Sassuolo |
| SSC Napoli | 15:00 | Genoa |
| Hellas Verona | 15:00 | Udinese |
| Crotone | 18:00 | Milan |
| Roma | 20:45 | Juventus |
| September 28, 2020 | ||
| Bologna | 20:45 | Parma |
| September 30, 2020 | ||
| Benevento | 18:00 | Inter Milan |
| Udinese | 18:00 | Spezia |
| Lazio | 20:45 | Atalanta |
| October 2, 2020 | ||
| Fiorentina | 20:45 | Sampdoria |
| October 3, 2020 | ||
| Sassuolo | 15:00 | Crotone |
| Genoa | 18:00 | Torino |
| Udinese | 20:45 | Roma |
