| September 25, 2020 | ||
| Hertha BSC | 20:30 | Eintracht Frankfurt |
| September 26, 2020 | ||
| Augsburg 1907 | 15:30 | Borussia Dortmund |
| Arminia Bielefeld | 15:30 | 1. FC Köln |
| Borussia Mönchengladbach | 15:30 | Union Berlin |
| 1. FSV Mainz 05 | 15:30 | Stuttgart |
| Bayer 04 Leverkusen | 15:30 | RB Leipzig |
| Schalke 04 | 18:30 | Werder Bremen |
| September 27, 2020 | ||
| TSG 1899 Hoffenheim | 15:30 | Bayern Munich |
| SC Freiburg | 18:00 | Wolfsburg |
| October 2, 2020 | ||
| Union Berlin | 20:30 | 1. FSV Mainz 05 |
| October 3, 2020 | ||
| Borussia Dortmund | 15:30 | SC Freiburg |
| Eintracht Frankfurt | 15:30 | TSG 1899 Hoffenheim |
| 1. FC Köln | 15:30 | Borussia Mönchengladbach |
| Werder Bremen | 15:30 | Arminia Bielefeld |
| Stuttgart | 15:30 | Bayer 04 Leverkusen |
| RB Leipzig | 18:30 | Schalke 04 |
| October 4, 2020 | ||
| Wolfsburg | 15:30 | Augsburg 1907 |
| Bayern Munich | 18:00 | Hertha BSC |
