| October 16, 2021 | ||
| Degerfors | 15:00 | Halmstad |
| Östersunds FK | 15:00 | Malmö |
| Sirius | 17:30 | Varberg |
| October 17, 2021 | ||
| Hammarby | 15:00 | AIK |
| Mjällby | 15:00 | Kalmar |
| IFK Göteborg | 17:30 | Örebro |
| October 18, 2021 | ||
| Häcken | 19:00 | Norrköping |
| Djurgården | 19:00 | Elfsborg |
| October 23, 2021 | ||
| Djurgården | 15:00 | Kalmar |
| Häcken | 17:30 | Halmstad |
| October 24, 2021 | ||
| Hammarby | 15:00 | Östersunds FK |
| Elfsborg | 15:00 | Sirius |
| Mjällby | 15:00 | IFK Göteborg |
| AIK | 17:30 | Norrköping |
| Varberg | 17:30 | Malmö |
| October 25, 2021 | ||
| Örebro | 19:00 | Degerfors |
| October 27, 2021 | ||
| Östersunds FK | 19:00 | Häcken |
| Sirius | 19:00 | Hammarby |
| Malmö | 19:00 | AIK |
| Kalmar | 19:00 | Varberg |
