| November 29, 2020 | ||
| Saint-Etienne | 1 - 1 | LOSC Lille Métropole |
| OGC Nice | 1 - 3 | Dijon |
| Monaco | 3 - 0 | Nîmes |
| Metz | 0 - 2 | Brest |
| Lorient | 0 - 1 | Montpellier Hérault SC |
| Lens | 1 - 3 | Angers SCO |
| Olympique Lyonnais | 3 - 0 | Stade de Reims |
| November 28, 2020 | ||
| Paris Saint-Germain | 2 - 2 | Girondins de Bordeaux |
| Olympique de Marseille | 3 - 1 | Nantes |
| November 27, 2020 | ||
| Strasbourg | 1 - 1 | Stade Rennais FC |
| November 25, 2020 | ||
| Lens | 1 - 1 | Nantes |
| November 22, 2020 | ||
| LOSC Lille Métropole | 4 - 0 | Lorient |
| Angers SCO | 0 - 1 | Olympique Lyonnais |
| Dijon | 0 - 1 | Lens |
| Stade de Reims | 0 - 1 | Nîmes |
| Montpellier Hérault SC | 4 - 3 | Strasbourg |
| Nantes | 1 - 1 | Metz |
| November 21, 2020 | ||
| Brest | 4 - 1 | Saint-Etienne |
| November 20, 2020 | ||
| Monaco | 3 - 2 | Paris Saint-Germain |
| Stade Rennais FC | 0 - 1 | Girondins de Bordeaux |
