| May 9, 2021 | ||
| Paços de Ferreira | 1 - 1 | Marítimo |
| May 7, 2021 | ||
| Boavista | 1 - 1 | Tondela |
| Famalicão | 1 - 0 | Santa Clara |
| May 6, 2021 | ||
| Farense | 2 - 2 | Vitoria Guimaraes |
| Benfica | 1 - 1 | Porto |
| Belenenses | 1 - 0 | Portimonense |
| Moreirense | 2 - 2 | Nacional |
| May 5, 2021 | ||
| Rio Ave | 0 - 2 | Sporting CP |
| SC Braga | 1 - 1 | Paços de Ferreira |
| Marítimo | 0 - 1 | Gil Vicente |
| May 1, 2021 | ||
| Sporting CP | 2 - 0 | Nacional |
| Portimonense | 0 - 0 | Rio Ave |
| Santa Clara | 3 - 3 | Boavista |
| Gil Vicente | 0 - 0 | Farense |
| April 30, 2021 | ||
| Porto | 3 - 2 | Famalicão |
| Tondela | 0 - 2 | Benfica |
| Vitoria Guimaraes | 2 - 0 | Moreirense |
| Paços de Ferreira | 1 - 0 | Belenenses |
| April 29, 2021 | ||
| Marítimo | 1 - 0 | SC Braga |
| April 27, 2021 | ||
| Farense | 1 - 1 | Portimonense |
