| September 19, 2020 | ||
| Sporting CP | 19:30 | Gil Vicente |
| September 26, 2020 | ||
| Marítimo | 16:30 | Tondela |
| Benfica | 19:30 | Moreirense |
| Boavista | 22:00 | Porto |
| September 27, 2020 | ||
| Farense | 16:30 | Nacional |
| Gil Vicente | 17:00 | Portimonense |
| Paços de Ferreira | 19:30 | Sporting CP |
| Rio Ave | 22:00 | Vitoria Guimaraes |
| September 28, 2020 | ||
| Belenenses | 20:45 | Famalicão |
| October 2, 2020 | ||
| Moreirense | 20:00 | Boavista |
| Vitoria Guimaraes | 22:15 | Paços de Ferreira |
| October 3, 2020 | ||
| Santa Clara | 17:00 | Gil Vicente |
| Porto | 19:30 | Marítimo |
| Tondela | 22:00 | SC Braga |
| October 4, 2020 | ||
| Nacional | 16:30 | Belenenses |
| Famalicão | 19:30 | Rio Ave |
| Benfica | 19:30 | Farense |
| Portimonense | 22:00 | Sporting CP |
