| January 29, 2022 | ||
| Ross County | 14:30 | Rangers |
| Hearts | 17:00 | Motherwell |
| Hibernian | 17:00 | Livingston |
| Aberdeen | 17:00 | St. Johnstone |
| Celtic | 17:00 | Dundee United |
| Dundee | 17:00 | St. Mirren |
| February 1, 2022 | ||
| Dundee | 21:45 | Dundee United |
| Hibernian | 21:45 | Hearts |
| Livingston | 21:45 | St. Johnstone |
| Ross County | 21:45 | Aberdeen |
| St. Mirren | 21:45 | Motherwell |
| February 2, 2022 | ||
| Celtic | 21:45 | Rangers |
| February 5, 2022 | ||
| Livingston | 17:00 | Aberdeen |
| St. Johnstone | 17:00 | Dundee United |
| Hibernian | 17:00 | St. Mirren |
| Dundee | 17:00 | Ross County |
| February 6, 2022 | ||
| Motherwell | 15:30 | Celtic |
| Rangers | 18:00 | Hearts |
