| November 30, 2020 | ||
| Real Betis | 0 - 2 | Eibar |
| November 29, 2020 | ||
| Real Sociedad | 1 - 1 | Villarreal |
| Celta Vigo | 3 - 1 | Granada |
| Getafe | 1 - 1 | Athletic Bilbao |
| Barcelona | 4 - 0 | Osasuna |
| November 28, 2020 | ||
| Real Madrid | 1 - 2 | Deportivo Alavés |
| Huesca | 0 - 1 | Sevilla |
| Valencia | 0 - 1 | Atlético de Madrid |
| Elche | 1 - 1 | Cádiz |
| November 27, 2020 | ||
| Real Valladolid | 1 - 1 | Levante |
| November 23, 2020 | ||
| Athletic Bilbao | 4 - 0 | Real Betis |
| November 22, 2020 | ||
| Deportivo Alavés | 2 - 2 | Valencia |
| Granada | 1 - 3 | Real Valladolid |
| Cádiz | 0 - 1 | Real Sociedad |
| Eibar | 0 - 0 | Getafe |
| November 21, 2020 | ||
| Atlético de Madrid | 1 - 0 | Barcelona |
| Sevilla | 4 - 2 | Celta Vigo |
| Villarreal | 1 - 1 | Real Madrid |
| Levante | 1 - 1 | Elche |
| November 20, 2020 | ||
| Osasuna | 1 - 1 | Huesca |
