| September 12, 2020 | ||
| Burnley | 01:00 | Manchester United |
| Manchester City | 01:00 | Aston Villa |
| November 28, 2020 | ||
| Manchester City | 17:00 | Burnley |
| Everton | 19:30 | Leeds United |
| West Bromwich Albion | 22:00 | Sheffield United |
| November 29, 2020 | ||
| Southampton | 16:00 | Manchester United |
| Chelsea | 18:30 | Tottenham Hotspur |
| Arsenal | 21:15 | Wolverhampton Wanderers |
| November 30, 2020 | ||
| Leicester City | 19:30 | Fulham |
| West Ham United | 22:00 | Aston Villa |
| December 4, 2020 | ||
| Aston Villa | 22:00 | Newcastle United |
| December 5, 2020 | ||
| Burnley | 14:30 | Everton |
| Manchester City | 17:00 | Fulham |
| West Ham United | 19:30 | Manchester United |
| Chelsea | 22:00 | Leeds United |
| December 6, 2020 | ||
| West Bromwich Albion | 14:00 | Crystal Palace |
| Sheffield United | 16:15 | Leicester City |
| Tottenham Hotspur | 18:30 | Arsenal |
| Liverpool | 21:15 | Wolverhampton Wanderers |
| December 7, 2020 | ||
| Brighton & Hov… | 22:00 | Southampton |
