| August 5, 2022 | ||
| Crystal Palace | 21:00 | Arsenal |
| August 6, 2022 | ||
| Fulham | 13:30 | Liverpool |
| AFC Bournemouth | 16:00 | Aston Villa |
| Newcastle United | 16:00 | Nottingham Forest |
| Tottenham Hotspur | 16:00 | Southampton |
| Leeds United | 16:00 | Wolverhampton Wanderers |
| Everton | 18:30 | Chelsea |
| August 7, 2022 | ||
| Leicester City | 15:00 | Brentford |
| Manchester United | 15:00 | Brighton & Hov… |
| West Ham United | 17:30 | Manchester City |
| August 13, 2022 | ||
| Manchester City | 16:00 | AFC Bournemouth |
| Wolverhampton Wanderers | 16:00 | Fulham |
| Southampton | 16:00 | Leeds United |
| Nottingham Forest | 16:00 | West Ham United |
| Brighton & Hov… | 16:00 | Newcastle United |
| Liverpool | 16:00 | Crystal Palace |
| Chelsea | 16:00 | Tottenham Hotspur |
| Aston Villa | 16:00 | Everton |
| Arsenal | 16:00 | Leicester City |
| Brentford | 16:00 | Manchester United |
